Monoclonal Anti-Plakoglobin (Catenin γ) antibody produced in mouse
clone 15F11, ascites fluid, buffered aqueous solution
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MDL number MFCD00164716
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Properties
| Related Categories | 1-1B, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies in Array, |
| species reactivity | human, bovine, canine |
| application(s) | immunocytochemistry: suitable using cultured cells |
| immunohistochemistry (frozen sections): suitable | |
| immunoprecipitation: suitable | |
| indirect immunofluorescence: 1:1,000 using cultured MDBK cells | |
| microarray: suitable | |
| western blot: 1:2,000 using cultured MDBK cells | |
| clone | 15F11, monoclonal |
| antibody form | ascites fluid |
| form | buffered aqueous solution |
| isotype | IgG1 |
| mol wt | antigen mol wt 85 kDa |
| contains | 15 mM sodium azide |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information | human ... JUP(3728) |
Description
Immunogen
recombinant chicken plakoglobin.
General description
Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas 2. Plakoglobin may function as a tumor suppressor in ovarian and breast cancers 3. Monoclonal anti-plakoglobin (catenin γ) antibody specifically binds to plakoglobin (85kDa band and a possibly lower band) by immunoblotting. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin.
Application
Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting 1. The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells).
Price and Availability
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