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P8692 Sigma

Paromomycin sulfate salt

plant cell culture tested, BioReagent

  • CAS Number 1263-89-4

  • Empirical Formula (Hill Notation) C23H45N5O14 · xH2SO4

  • Molecular Weight 615.63 (free base basis)

  •  Beilstein Registry Number 5715182

  •  PubChem Substance ID 24898967

  • Popular Documents:  Specification Sheet (PDF)  

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Properties

Related Categories Aminoglycosides, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S,
InChI Key   OYJABWUHUYVDMJ-UDXJMMFXSA-N
product line   BioReagent
form   powder
application(s)   cell culture | plant: suitable
solubility   H2O: soluble50 mg/mL, clear, colorless to faintly yellow
suitability   plant cell culture tested
Featured Industry   Agriculture
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria

Description

Packaging

5g,25g

Application

Paromomycin, monomycin, is an aminoglycoside antibiotic used to select genetically transformed plants and plant cells.

Biochem/physiol Actions

Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.

Other Notes

Keep container tightly closed in a dry and well-ventilated place

Protocols & Applications

Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Protocols

Antibiotics - Plant Tissue Culture Protocol

In general, antibiotics require storage in a refrigerator or freezer. Aminoglycosides (e.g. kanamycin) are hygroscopic and should be stored in a desiccator. Storage of many powdered antibiotics at -2...
Keywords: Adsorption, Antibiotics, Antifungals, Condensations, Molecular biology

Related Content

Antibiotic Selection Guide

1Application Key: CC = Callus Culture; PR = plant regeneration; EC = cotyledon, hypocotyl, or leaf disc culture; TS = transformant selection; SE = somatic embryogenesis; SSC = stem selection culture;...
Keywords: Antibiotics, Cell culture

Peer-Reviewed Papers
15

References

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