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P8727 Sigma

Palmityl trifluoromethyl ketone

phosholipase A2 inhibitor

Synonym: PACOCF3, Pentadecyl trifluoromethyl ketone

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Properties

Related Categories Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, P to Q,
InChI Key   MAHYXYTYTLCTQD-UHFFFAOYSA-N
concentration   10 mg/mL in ethanol
storage temp.   −20°C

Description

Packaging

5 mg in serum bottle

Biochem/physiol Actions

Reversible inhibitor of calcium-dependent phospholipase A2 (IC50 = 3.8 μM). Unlike other PLA2 inhibitors studied, PACOCF3 at 50 μM induced an increase in intracellular [Ca2+], and at 10 μM, enhanced calcium-ion influx induced by ATP and bradykinin.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany 
2
Flash Point(F) 
57.2 °F
Flash Point(C) 
14 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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