Ammonium pyrrolidinedithiocarbamate ~99%

Properties

Related Categories	A-AM, Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience, Core Bioreagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, L to O, NOS Regulators, Nitric Oxide Metabolism, Nitric Oxide Synthase, Nitric Oxide Synthase Regulators, Nitric Oxide and Cell Stress, Research Essentials More...
assay	~99%
mp	153-155 °C(lit.)
storage temp.	2-8°C
Gene Information	human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846), RELA(5970)

Description

Frequently Asked Questions

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Biochem/physiol Actions

Prevents induction of nitric oxide synthetase by inhibiting translation of NOS mRNA; induces apoptosis in rat smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells.

Packaging

1, 5, 25, 100 g in glass bottle

Price and Availability

Related Papers

Differential Regulation Of Interleukin-1 Receptor-associated Kinase-1 (IRAK-1) And IRAK-2 By MicroRNA-146a And NF-{kappa}B In Stressed Human Astroglial Cells And In Alzheimer Disease. Cui, J.G., et al. J. Thorac. Cardiovasc. Surg. 285, 38951-60, (2010)

Documents

Certificate of Analysis

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FT-IR Condensed Phase

FT-IR Raman

Safety Information

Symbol	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes (Europe)	Xi
Risk Statements (Europe)	36/37/38
Safety Statements (Europe)	26-36
WGK Germany	3

Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Papers

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Differential Regulation Of Interleukin-1 Receptor-associated Kinase-1 (IRAK-1) And IRAK-2 By MicroRNA-146a And NF-{kappa}B In Stressed Human Astroglial Cells And In Alzheimer Disease. Cui, J.G., et al. J. Thorac. Cardiovasc. Surg. 285, 38951-60, (2010)

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Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. Yasuhiro Horita et al Bioorg. Med. Chem. Lett. 21, 899-903, (2011)

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Pyrrolidine dithiocarbamate inhibits induction of nitric oxide synthase activity in rat alveolar macrophages. Sherman, M. P., et al. Biochem. Biophys. Res. Commun. 191, 1301-1308, (1993)

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Beil. 20,V,1,331

Corp MSDS 1 (2), 3014:A / FT-IR 2 (1), 1413:B / FT-IR 1 (1), 834:C / IR-Spectra (2), 439:D / IR-Spectra (3), 495:G / NMR-Reference 2 (1), 691:A / RegBook 1 (1), 979:C / Sigma FT-IR 1 (2), 875:B / Structure Index 1, 152:D:8