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  • P9357 - Anti-Potassium Channel Kv1.5 antibody produced in rabbit

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P9357 Sigma

Anti-Potassium Channel Kv1.5 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Ion Channels, Antibodies to Potassium Channels,
species reactivity   rat, mouse
application(s)   western blot (chemiluminescent): 1:200-1:400
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   mouse ... Kcna5(16493)
rat ... Kcna5(25470)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

GST fusion protein from the C-terminal of mouse potassium channel Kv1.5 corresponding to amino acids 513-602.

General description

Pivotal role of potassium channel is maintaining cell volume, membrane potential and neuronal excitability. Two families of potassium channel exists- one with inwardly rectifying potassium channel and the other with voltage sensing (KV) big conductance, calcium activated (BKCA ) small conductance and calcium activated (SK) potassium channel. KV1.5 channel is O2 sensitive, so hypoxia inhibits the expression of KV1.5 channel through 15-HETE pathway. Anti-Potassium Channel Kv1.5 antibody reacts specifically with full length Kv1.5 protein of rat and mouse.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose and 0.05% sodium azide.

Application

Anti-Potassium Channel Kv1.5 antibody can be used in immunocytochemistry, immunoblotting and immunofluorescence.

Price and Availability


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