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P9953 - L-α-Phosphatidyl-D-myo-inositol 3,4,5-triphosphate, dioctanoyl

P9953 Sigma

L-α-Phosphatidyl-D-myo-inositol 3,4,5-triphosphate, dioctanoyl

DOWNLOAD MSDS (PDF)

Empirical Formula (Hill Notation) C₂₅H₅₀O₂₂P₄
Molecular Weight 826.55
MDL number MFCD02259165
PubChem Substance ID 24898933
Popular Documents: Specification Sheet (PDF)

L-α-Phosphatidyl-D-myo-inositol 3,4,5-triphosphate, dioctanoyl

Properties

Related Categories	3-Phosphoinositide-dependent Protein Kinase (PDK), Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Glycerophosphoinositols, Glycerophospholipid Metabolism, Glycerophospholipids, Inositol Phosphates, Kinase and Phosphatase Substrates, Kinase/Phosphatase Biology, Lipids, Lipids in Cell Signaling, Metabolic Pathways, Metabolomics, P, PI3K-Akt-mTOR Enzyme Regulators, PTEN, Peptides and Proteins, Peptides for Cell Biology, Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology, Substrates by Enzyme, Tumor Growth Regulation More...
solubility	H₂O: soluble
storage temp.	−20°C

Description

Biochem/physiol Actions

Signaling lipid; activates PDK1 (3-phosphoinositide-dependent protein kinase), which is necessary, but not sufficient, for the activation of PKB/Akt. PDK1 also phosphorylates and activates p70^S6k.

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Related Papers

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Alessi, D.R, et al. Curr. Biol. 7, 261-269, (1997)

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