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PENNA Sigma

Penicillin G sodium salt

~1650 U/mg

Synonym: Benzylpenicillin sodium salt

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics N-S, Apoptosis and Cell Cycle, Biochemicals and Reagents,
InChI Key   FCPVYOBCFFNJFS-LQDWTQKMSA-M
form   powder
solubility   H2O: soluble100 mg/mL
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   2-8°C

Description

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Caution

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.

Packaging

1mu,10mu,100mu

Application

Penicillin G is a narrow spectrum antibiotic. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G sodium salt is used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility . It is used in cell culture alone as well as in combination with streptomycin and other antibiotics.

General description

Penicillin G is a narrow spectrum antibiotic. It is effective against Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Product contains Penicillin

Protocols & Applications

Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Price and Availability


Laboratory Gloves

All labs need water
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
XH9800000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Inhibition of Cell Wall Biosynthesis by Antibiotics

Antibiotics are molecules that specifically target and kill cells. The term antibiotic is frequently used interchangeably with the word antibacterial, but antiviral, antifungal and antineoplastic com...
BioFiles 2006, 1.4, 7.
Keywords: Antibiotics, Antifungals, Antivirals, Building blocks, Glycosylations, Metabolism

Peer-Reviewed Papers
15

References

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