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Q2128 Sigma

Quisqualic acid

powder

Synonym: β-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine

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Properties

Related Categories AMPA/Kainate Agonists, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Ion Channels,
InChI Key   ASNFTDCKZKHJSW-REOHCLBHSA-N
form   powder
color   white to off-white
solubility   ethanol: <0.17 mg/mL
  H2O: soluble0.5 mg/mL
  0.1 M HCl: soluble1.4 mg/mL
  1 M NH4OH: soluble20 mg/mL
  organic solvents: insoluble
storage temp.   2-8°C
Gene Information   rat ... Gria1(50592), Grik1(29559), Grin2a(24409), Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418)

Description

Biochem/physiol Actions

Active enantiomer of quisqualic acid; excitatory amino acid at glutamate receptors.

Packaging

1, 5 mg in glass bottle

10, 25 mg in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

General description

Quisqualate/ Quisqualic acid is obtained from the fruits and seeds of Quisqualis chinensis. It is an agonist at two subsets of excitatory amino acid receptors metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores and, ionotropic receptors that directly control membrane channels.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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