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Q3625 Sigma

Quinidine

anhydrous

  • CAS Number 56-54-2

  • Empirical Formula (Hill Notation) C20H24N2O2

  • Molecular Weight 324.42

  •  Beilstein Registry Number 91866

  •  EC Number 200-279-0

  •  MDL number MFCD00135581

  •  PubChem Substance ID 24899331

  • Popular Documents:  FTNMR (PDF)  

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Asymmetric Synthesis, Bayer, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
grade   anhydrous
InChI Key   LOUPRKONTZGTKE-LHHVKLHASA-N
impurities   ≤20% Dihydroquinidine (according to USP specifications., actual content given on label)
mp   168-172 °C(lit.)
originator   Bayer
Gene Information   human ... ABCB1(5243), CYP2D6(1565), CYP3A4(1576), KCNH1(3756)
mouse ... Abcb1a(18671), Abcb1b(18669)
rat ... Cyp2d1(266684), Cyp2d2(25053), Cyp2d3(24303), Cyp2d4v1(171522)

Description

Biochem/physiol Actions

Class IA antiarrhythmic; potassium channel blocker.

Packaging

5, 25 g in glass bottle

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
VA4725000
Protocols & Articles

Articles

Discover Bioactive Small Molecules for ADME/Tox

A significant number of drugs that fail in clinical trials have been associated with safety issues, including unexpected drug-drug interactions (DDI) or lack of efficacy due to poor pharmacokinetics....
Keywords: Absorption, Bioactive small molecules, Clinical, Metabolism

Discover Bioactive Small Molecules for Ion Channels Research

Ion transport across the relatively impermeable lipid bilayer of the cell membrane is accomplished via membrane proteins known as ion channels, pumps and transporters. Ion channels are gated pores an...
Keywords: Biological processes, Cell signaling, Diseases, Hormones, Ligands, Neurotransmitters

Peer-Reviewed Papers
15

References

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