|Related Categories||Biochemicals and Reagents, Cancer Metabolism, Cancer Research, Cell Biology, Cell Signaling and Neuroscience,|
|storage temp.||room temp|
Quercetin is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. Quercetin may also inhibit fatty acid synthase activity.
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|Precautionary statements||P301 + P310|
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|Risk Statements (Europe)||25|
|Safety Statements (Europe)||45|
|RIDADR||UN 2811 6.1 / PGIII|
Proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sour...
Keywords: Apoptosis, Cancer, Carboxylations, Catalysis, Gene expression, Glycolysis, Metabolism, Oxidations, PAGE, Phosphorylations
It is well established that the brain can sense and react to peripheral insults through the rapid induction of fever and other neuroendocrine changes in response to events such as infection and tissu...
Scott Hauser, Technology Transfer Specialist, Sigma® Life Science
Biofiles, Vol. 8, No. 19
Keywords: Adhesion, Biofiles, Central Nervous System, Diseases, Events, Gene expression, Inflammation, Neurodegenerative Diseases, Reductions, Type
Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet. Stewart LK Metabolism 57(7 Suppl 1), S39-46, (2008)
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