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R0283 Sigma

Ropivacaine hydrochloride monohydrate

≥98% (HPLC)

Synonym: (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride monohydrate, (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide hydrochloride monohydrate, Naropin hydrochloride monohydrate

  • CAS Number 132112-35-7

  • Empirical Formula (Hill Notation) C17H26N2O · HCl · H2O

  • Molecular Weight 328.88

  •  MDL number MFCD00946578

  •  PubChem Substance ID 329823983

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Properties

Related Categories Approved Therapeutics/Drug Candidates, AstraZeneca, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
InChI Key   VSHFRHVKMYGBJL-CKUXDGONSA-N
assay   ≥98% (HPLC)
form   powder
optical activity   [α]/D -9 to -12, c = 1 in methanol
color   white to off-white
solubility   H2O: soluble5 mg/mL, clear
originator   AstraZeneca
storage temp.   2-8°C

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Local anaesthetic with less cardiotoxicity than bupivacaine; causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Discover Bioactive Small Molecules for Ion Channels Research

Ion transport across the relatively impermeable lipid bilayer of the cell membrane is accomplished via membrane proteins known as ion channels, pumps and transporters. Ion channels are gated pores an...
Keywords: Biological processes, Cell signaling, Diseases, Hormones, Ligands, Neurotransmitters

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