• USA Home
  • R0775 - RANK/Fc Chimera from mouse

EMAIL THIS PAGE TO A FRIEND
R0775 Sigma

RANK/Fc Chimera from mouse

≥95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, cell culture tested

Synonym: Osteoclast differentiation receptor, ODFR, Receptor activator of NF-κB

Purchase

Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, RANK, Osteoprotegerin and TRAIL,
recombinant   expressed in NSO cells
assay   ≥95% (SDS-PAGE)
form   lyophilized powder
impurities   endotoxin, tested
suitability   cell culture tested
storage temp.   −20°C
Gene Information   mouse ... Tnfrsf11a(21934)

Description

Analysis Note

The biological activity is measured by its ability to inhibit TRANCE-induced osteoclast differentiation in mouse splenocytes.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Biochem/physiol Actions

TRANCE (TNF-related activation-induced cytokines, also known as RANK ligand, osteoprotegerin ligand and osteoclast differentiation factor) is the ligand for RANK. The biological functions mediated through RANK include activation of NF-κB and c-jun N-terminal kinases, enhancement of T cell growth and dentritic cell function, induction of osteoclastogenesis, and lymph node genesis. Soluble RANK is able to block TRANCE-induced biological activity.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?