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R108 Sigma

Ro 41-0960

solid

Synonym: 2′-Fluoro-3,4-dihydroxy-5-nitrobenzophenone

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Catechol-O-methyltransferase, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   RQPAUNZYTYHKHA-UHFFFAOYSA-N
form   solid
storage condition   protect from light
color   yellow
solubility   H2O: slightly soluble <0.7 mg/mL
  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble1.0 mg/mL
  ethanol: soluble
storage temp.   2-8°C
Gene Information   human ... COMT(1312)

Description

Biochem/physiol Actions

Specific, reversible, orally-active COMT-inhibitor.

Caution

Store tightly sealed at 4 °C, protected from exposure to light.

Packaging

25, 100 mg in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
PC4952300

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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