EMAIL THIS PAGE TO A FRIEND

R1408 Sigma

RU7

≥98% (HPLC)

Synonym: 5-[(2,3-Dibromo-5-ethoxy-4-hydroxyphenyl)methylene]-4-oxo-2-thioxo-3-thiazolidineacetic acid

  • CAS Number 355400-87-2

  • Empirical Formula (Hill Notation) C14H11Br2NO5S2

  • Molecular Weight 497.18

  •  MDL number MFCD01963653

Purchase

Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DNA-RNA Transcription Regulators,
assay   ≥98% (HPLC)
form   powder
color   yellow
solubility   DMSO: ≥20 mg/mL
storage temp.   2-8°C

Description

Biochem/physiol Actions

RU7 is a selective inhibitor of bacterial β-clamp interaction with DNA polymerase POL III, and an inhibitor of a DNA polymerase sliding clamp. Sliding clamps are proteins which function with diverse DNA polymerases, repair factors, and cell cycle-control proteins. RU7 binds to the peptide-binding pocket of the β-clamp and selectively inhibits Pol III, compared with Pol II and Pol IV.

Price and Availability


DISCOVER Bioactive Small Molecules

Duolink Webinar

Customers Also Viewed

Menadione

crystalline

BioReagent, suitable for fluorescence, ≥90% (sum of isomers, HPCE)

Safety & Documentation

Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?