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R2027 Sigma

Ral B human

recombinant, expressed in E. coli, buffered aqueous glycerol solution

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, G Protein Function, G Protein Function Enzymes, G Proteins and Cyclic Nucleotides More...
recombinant   expressed in E. coli
form   buffered aqueous glycerol solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... RALB(5899)

Description

Application

Can be used as a control in immunoblotting and in protein binding assays.

Other Notes

GST-tagged Ras-like fusion protein

Physical form

Supplied as a solution in 50 mM Tris, pH 7.5, containing 150 mM sodium chloride, 10 mM magnesium chloride, 1 mM DTT, and 10% glycerol.

Biochem/physiol Actions

Ral B (21 kDa, native), a member of the Ras-like GTP binding protein family, is a crucial link in intracellular signaling cascades.

Ral B has been implicated in invasion and metastasis of human cancer cells. Reports have shown that depletion of Ral B by siRNA results in significantly reduced migration rates of tumor cells, while constitutively active Ral B promoted migration.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

WGK Germany 
1

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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