R2408
Sigma
Rosiglitazone
≥98% (HPLC)
DOWNLOAD MSDS (PDF)Synonym:
5-
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CAS Number 122320-73-4
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Linear Formula C18H19N3O3S
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Molecular Weight 357.43
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MDL number MFCD00871760
Properties
| Related Categories | Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression, |
| assay | ≥98% (HPLC) |
| ≥98% (HPLC) | |
| form | powder |
| solubility | DMSO: ≥10 mg/mL |
| storage temp. | 2-8°C |
Description
Biochem/physiol Actions
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.
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