Synonym: Retinol acetate, Vitamin A acetate
|Related Categories||Cell Biology, Nutrition Research, Vitamin A, Vitamins|
Activity based on HPLC comparison to USP standard.
10, 100 g in glass bottle
Dispersion in cornstarch-gelatin matrix. Oil dispersible
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications.
Customers Also Viewed
synthetic, crystalline solid or supercooled liquid
solid or viscous liquid, BioReagent, synthetic, suitable for cell culture
concentrate (~50% (w/w) in peanut oil), ~1500 U/mg
potency: 1,600,000-1,800,000 USP units per g
Certificate of Analysis
Certificate of Origin
|Personal Protective Equipment||Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||63-38|
|Safety Statements (Europe)||36/37|
All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apopt...
BioFiles 2008, 3.9, 12.
Keywords: Apoptosis, Cancer, Cell proliferation, Cellular processes, Chromatin immunoprecipitation, Condensations, Degradations, Diseases, Gene expression, Hormones, Immunoprecipitation, Ligands, Metabolism, Oxidations, Phosphorylations, Polymerase chain reaction, Teratogens, Transcription, Ubiquitinations, Vitamins
Intake of high levels of vitamin A and polyunsaturated fatty acids during different developmental periods modifies the expression of morphogenesis genes in European sea bass (Dicentrarchus labrax). Villeneuve, L.A.N., et al. Br. J. Nutr. 95, 677-87, (2006)
Surface activity of surfactant spiked with vitamin A. Bronshtein V, Venkatesh V, et al. Drug Des. Discovery 2, 145-150, (2009)
Vitamin A is systemically bioavailable after intratracheal administration with surfactant in an animal model of newborn respiratory distress. Singh AJ, Bronshtein V, Khashu M, et al. Pediatr. Res. 67, 619-623, (2010)
Population deworming every 6 months with albendazole in 1 million pre-school children in north India: DEVTA, a cluster-randomised trial. Awasthi S, Peto R, Read S, et al. Lancet 381(9876), 1478-86, (2013)
Vitamin A supplementation every 6 months with retinol in 1 million pre-school children in north India: DEVTA, a cluster-randomised trial. Awasthi S, Peto R, Read S, et al. Lancet 381(9876), 1469-77, (2013)
Quantification of β-carotene, retinol, retinyl acetate and retinyl palmitate in enriched fruit juices using dispersive liquid-liquid microextraction coupled to liquid chromatography with fluorescence detection and atmospheric pressure chemical ionization-mass spectrometry. Viñas P, Bravo-Bravo M, López-García I, et al. J. Chromatogr. A 1275, 1-8, (2013)
Lemon (Citrus limon, Burm.f.) essential oil enhances the trans-epidermal release of lipid-(A, E) and water-(B6, C) soluble vitamins from topical emulsions in reconstructed human epidermis. Valgimigli L, Gabbanini S, Berlini E, et al. Int. J. Cosmet. Sci. 34(4), 347-56, (2012)
Nanoscale domains with nematic order in supercooled vitamin-A acetate: molecular dynamics studies. Wojnarowska Z, Paluch M, Wlodarczyk P, et al. Phys. Rev. E. Stat. Nonlin. Soft Matter Phys. 83(5 Pt 1), 051502, (2011)
An optimized and validated RP-HPLC/UV detection method for simultaneous determination of all-trans-retinol (vitamin A) and alpha-tocopherol (vitamin E) in human serum: comparison of different particulate reversed-phase HPLC columns. Khan A, Khan MI, Iqbal Z, et al. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 878(25), 2339-47, (2010)
A randomized controlled trial to assess the impact of dietary energy sources, feed supplements, and the presence of super-shedders on the detection of Escherichia coli O157:H7 in feedlot cattle using different diagnostic procedures. Cernicchiaro N, Pearl DL, McEwen SA, et al. Foodborne Pathog. Dis. 7(9), 1071-81, (2010)
Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance. Maeda T, Maeda A, Matosky M, et al. Invest. Ophthalmol. Vis. Sci. 50(10), 4917-25, (2009)
Preparation, in vitro and in vivo evaluation of solid-state self-nanoemulsifying drug delivery system (SNEDDS) of vitamin A acetate. Taha EI, Al-Suwayeh SA, and Anwer MK J. Drug Target. 17(6), 468-73, (2009)
Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate. Maeda T, Cideciyan AV, Maeda A, et al. Hum. Mol. Genet. 18(12), 2277-87, (2009)
Plasma turnover of 3,4-didehydroretinol (vitamin A2) increases in vitamin A-deficient rats fed low versus high dietary fat. Escaron AL, Green MH, and Tanumihardjo SA J. Lipid Res. 50(4), 694-703, (2009)
Application of an allosteric model to describe the interactions among retinol binding protein 4, transthyretin, and small molecule retinol binding protein 4 ligands. Coward P, Conn M, Tang J, et al. Anal. Biochem. 384(2), 312-20, (2009)
Small quantities of carotenoid-rich tropical green leafy vegetables indigenous to Africa maintain vitamin A status in Mongolian gerbils ( Meriones unguiculatus). Ejoh RA, Dever JT, Mills JP, et al. Br. J. Nutr. 103(11), 1594-601, (2010)
Vitamin A and C compounds permitted in supplements differ in their abilities to affect cell viability, DNA and the DNA nucleoside deoxyguanosine. Bergström T, Bergman J, Möller L. Mutagenesis 26(6), 73-44, (2011)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?