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R5143 Sigma

Rutin hydrate

≥94% (HPLC), powder

Synonym: Quercetin-3-rutinoside hydrate, Vitamin P hydrate

  • CAS Number 207671-50-9

  • Empirical Formula (Hill Notation) C27H30O16 · xH2O

  • Molecular Weight 610.52 (anhydrous basis)

  •  Beilstein Registry Number 75455

  •  EC Number 205-814-1

  •  MDL number MFCD01319140

  •  PubChem Substance ID 24899379

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Description

Biochem/physiol Actions

A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in nuclear DNA caused by hepatocarcinogens aflatoxin B1 and N-nitrosodiumethylamine. This protection from DNA damage was found to be due to a reduction in the induction of repair enzymes polymerase, DNA polymerase β and DNA ligase. Since DNA damage and inefficient repair are thought to initiate the process of carcinogenesis, effects of rutin on these functions suggests a protective role of this flavonoid against carcinogenesis induced by chemical carcinogens.

Protocols & Applications

Ginkgo (Ginkgo biloba) Plant Profile: bioactives, mechanism of action, references

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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