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R5145 Sigma

Anti-Rsk1 antibody produced in rabbit

whole antiserum

Synonym: Anti-p90rsk

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Primary Antibodies,
species reactivity   mouse, rat, human
application(s)   microarray: suitable
  western blot: 1:4,000 using mouse NIH 3T3 fibroblast cell lysate and rat brain extract
clone   polyclonal
antibody form   whole antiserum
mol wt   antigen mol wt 80 kDa
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... RPS6KA1(6195)
mouse ... Rps6ka1(20111)
rat ... Rps6ka1(81771)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

Synthetic peptide corresponding to amino acids 707-723 of human Rsk1 coupled to KLH.

General description

Rsk1 is a ubiquitously expressed, mitogen-activated protein that belongs to the serine/threonine protein kinases family. It has a pivotal role in facilitating MEK-MAP kinase cell survival signaling and supressing pro-apoptotic function of BAD by phosphorylating it. Anti-Rsk1 antibody can be used for studying differential tissue expression of (p90rsk) and its intracellular localization in normal and neoplastic tissues. It can also be used to detect (p90rsk). Rabbit anti-Rsk1 antibody reacts specifically with an intermediate phosphorylated form of Rsk1 in mouse fibroblasts cell lysates and rat brain extracts.

Application

Anti-Rsk1 antibody can be used in microarray and western blotting.

Price and Availability


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