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R7882 Sigma

Retinyl acetate

solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

Synonym: Retinol acetate, Vitamin A acetate

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Properties

Related Categories Bioactives and Supplements for Stem Cell Expansion, Bioactives/Supplements, Cell Biology, General Stem Cell Biology, Nutrition Research,
biological source   synthetic
InChI Key   QGNJRVVDBSJHIZ-QHLGVNSISA-N
product line   BioReagent
form   solid or viscous liquid
potency   ~2,800,000 I.U. per g
mp   57-58 °C
solubility   absolute ethanol: soluble25 mg/mL (lit.)
suitability   suitable for cell culture
storage temp.   −20°C

Description

Other Notes

All trans

Packaging

1, 5 g in glass bottle

Preparation Note

The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid.

General description

Retinyl-acetate (aka Vitamin A) is found in classical media formulations such as M-199; NCTC-109 and William’s Medium E. Vitamin A is a component of serum use to supplement classical media, consequently most serum containing cell culture systems receive some level of vitamin A. The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
VH6825000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Retinoic Acid and Gene Expression

All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apopt...
BioFiles 2008, 3.9, 12.
Keywords: Apoptosis, Cancer, Cell proliferation, Cellular processes, Chromatin immunoprecipitation, Condensations, Degradations, Diseases, Gene expression, Hormones, Immunoprecipitation, Ligands, Metabolism, Oxidations, Phosphorylations, Polymerase chain reaction, Sequences, Teratogens, Transcription, Type, Ubiquitinations, Usage, Vitamins

Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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