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R8875 Sigma

Rotenone

≥95%

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cell Stress, Mitochondrial Inhibitors, Nitric Oxide and Cell Stress More...
InChI Key   JUVIOZPCNVVQFO-HBGVWJBISA-N
assay   ≥95%
bp   210-220 °C/0.5 mmHg(lit.)
mp   159-164 °C(lit.)

Description

Packaging

1, 5, 10, 25 g in glass bottle

Biochem/physiol Actions

Inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.

Inhibitor of mitochondrial electron transport. Neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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