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Recombinant DNA, 2nd Edition

  •  ISBN-10 0-7167-2282-8

  •  ISBN-13 978-0-7167-2282-3

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publication info   J. Watson, et al., W.H. Freeman, 1992, 626 pp., soft cover
mfr. no.   Freeman

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The application of recombinant DNA techniques to biology is bringing about a revolution in our understanding of living organisms. The aim of this edition is to show how recombinant DNA techniques have led to the explosion in our knowledge of fundamental processes.

Table of Contents

I. DEVELOPMENT OF RECOMBINANT DNA TECHNOLOGY
1. Establishing the Role of Genes within Cells
2. DNA is the Primary Genetic Material
3. Elucidation of the Genetic Code
4. The Genetic Elements that Control Gene Expression
5. Methods of Creating Recombinant DNA Molecules
II. ANALYSIS OF CLONED GENES
6. The Polymerase Chain Reaction
7. Isolation of Cloned Genes
8. The Complexity of the Genomes
9. Controlling Eukaryotic Gene Expression
10. Movable Genes
III. NEW TOOLS FOR STUDYING GENE FUNCTION
11. In Vitro Mutagenesis
12. Transferring Genes into Mammalian Cells
13. Using Yeast to Study Eukaryotic Gene Function
14. The Introduction of Foreign Genes into Mice
15. Genetic Engineering of Plants
IV. ANALYSIS OF IMPORTANT BIOLOGICAL PROCESSES USING RECOMBINANT DNA
16. Molecules of Immune Recognition
17. Moving Signals Across Membranes
18. Oncogenes and Anti-Oncogenes
19. Molecular Analysis of the Cell Cycle
20. The Genes that Control the Development of Drosophila
21. The Genes Behind the Functioning of the Brain
22. Recombinant DNA and Evolution
V. APPLICATION OF RECOMBINANT DNA TO BIOTECHNOLOGY
23. Recombinant DNA in Medicine and Industry
24. Generation of Agriculturally Important Plants and Animals
25. Marshalling Recombinant DNA to Fight AIDS
VI. IMPACT OF RECOMBINANT DNA ON HUMAN GENETICS
26. Mapping and Cloning Human Disease Genes
27. DNA-based Diagnosis of Genetic Diseases
28. Working Toward Human Gene Therapy
29. Studying Whole Genomes
30. The Human Genome Initiative--Finding All the Human Genes

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