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S0756 Sigma

Sphingomyelin

from chicken egg yolk, ≥95%

Synonym: N-Acyl-4-sphingenyl-1-O-phosphorylcholine, N-Acyl-D-sphingosine-1-phosphocholine

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Ceramide phosphocholines (sphingomyelins), Lipids, Metabolic Pathways,
biological source   from chicken egg yolk
assay   ≥95%
solubility   chloroform/methanol: soluble50 mg/mL, clear, colorless to faintly yellow (1:1)
storage temp.   −20°C

Description

Packaging

50, 100, 500 mg in poly bottle

Quality

Contains primarily palmitic acid.

Application

Sphingomyelin is suitable for use:
• in the preparation of standard during the enzymatic measurement of plasma sphingomyelin levels
• to study the binding of Vascular Anticoagulant α (VAC α) to planar phospholipid bilayers
• to perform fluorescence polarization of PC16 (N-[α-N-palmitoyl-ε-N-(4-nitrobenz-2-oxa-1,3-diazole)-L-lysine]-2-aminoethanol-N- (trimethylaminoethanol) phosphate) in dispersions of co-sonicated lecithin and sphingomyelin
• for reconstitution of viral ion channel protein M2 into liposomes
• as a standard sample to define spectral fingerproint using Time-of-flight secondary ion mass spectrometry (ToF-SIMS)
• to evaluate the contribution of various phospholipids to the formation of foam in the amniotic fluid

Biochem/physiol Actions

Sphingomyelin is the second most abundant lipid and major sphingolipid component of HDL and the plasma membrane. It forms cholesterol-enriched lipid rafts. It has a key role in the availability of plasma membrane-free cholesterol.

General description

Sphingomyelin (SM) is a principal sphingolipid in mammalian cell membranes. Its biological functions have been studied.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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