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  • S1300 - Monoclonal Anti-L-Selectin (CD62L) antibody produced in mouse

S1300 Sigma

Monoclonal Anti-L-Selectin (CD62L) antibody produced in mouse

2 mg/mL, clone FMC46, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-L-Selectin, Monoclonal Anti-CD62L


Related Categories Alphabetical Index, Analytical Cytology, Antibodies, Antibodies for Cell Biology, Antibodies for Hematopoietic Stem Cells,
species reactivity   human
application(s)   flow cytometry: suitable
  immunohistochemistry (frozen sections): suitable
clone   FMC46, monoclonal
concentration   2 mg/mL
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG2b
mol wt   antigen mol wt 74-95 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... SELL(6402)
biological source   mouse
conjugate   unconjugated



human PHA-activated peripheral blood mononuclear cells.

Antigen Background

CD62L, a glycoprotein and member of the selectin family of adhesion receptors, is constitutively expressed on all classes of leukocytes including lymphocytes, monocytes, and polymorphonuclear cells. It is expressed on myeloid progenitor cells, erythroid precursor cells, and some thymocytes.

Physical form

Solution, 0.2 μm filtered, in 0.01 M phosphate buffered saline, pH 7.4.


Recognizes the CD62L (L-Selectin, LAM-1, Leu8, TQ1, LECAM-1, LECCAM-1, DREG) surface antigen. The antibody recognizes an epitope localized to the lectin domain. It inhibits "rolling" interactions and significantly reduces the binding of FITC-yeast phosphomannan monoester core polysaccharide to lymphocytes, monocytes and neutrophils.
5th Workshop: Code No. S061

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