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S159 Sigma

R(−)-SCH-12679 maleate salt

solid

Synonym: R(−)-1-Phenyl-2,3,4,5-tetrahydro-1H-7,8-dimethoxy-3-benzazepine

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Properties

Related Categories Antagonists, Cell Biology, Cell Signaling and Neuroscience, Dopaminergics, Neuroscience,
InChI Key   TYNKKGLBKXZIHX-XLOMBBFOSA-N
form   solid
optical activity   [α]22/D −11.6°, c = 1.1 in H2O(lit.)
color   white
solubility   DMSO: soluble14 mg/mL
  H2O: soluble17.3 mg/mL
  ethanol: soluble4 mg/mL
  0.1 M HCl: >40 mg/mL
Gene Information   human ... DRD1(1812)

Description

Legal Information

Sold with the permission of Schering-Plough.

Application

R(-)-SCH-12679 maleate salt may be used in D1-dopamine receptor-mediated cell signaling studies.

Biochem/physiol Actions

SCH-12679 is a benzazepine compound and a psychoactive drug that antagonizes D1-dopamine receptor. It reduces the D1-induced locomotor activity and self-mutilation in rats. SCH-12679 decreased aggressiveness and hyperactive behavior in mentally deficient patients.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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