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S1875 Sigma

(−)-Scopolamine hydrobromide trihydrate

≥98% (HPLC), powder

Synonym: Hyoscine hydrobromide, Scopine tropate

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Properties

Related Categories Alkaloid, Antagonists, Antitumor Agents, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
InChI Key   LACQPOBCQQPVIT-SEYKEWMNSA-N
assay   ≥98% (HPLC)
form   powder
optical activity   [α]25/D −24 to −26°, c = 5 in H2O(lit.)
color   white to off-white
mp   195-199 °C (dry matter)(lit.)
solubility   H2O: soluble50 mg/mL
Gene Information   human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Description

Packaging

1, 5, 25 g in glass bottle

Biochem/physiol Actions

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


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Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1544PSN2 6.1 / PGIII
WGK Germany 
1
RTECS 
YM4730000
Protocols & Articles

Articles

Discover Bioactive Small Molecules for Neuroscience

The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is ...
Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters

Peer-Reviewed Papers
15

References

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