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S2437 Sigma

SCF Soluble Receptor human

>95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

Synonym: CD117, SCFsR, Stem Cell Factor Soluble Receptor

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Description

Analysis Note

The bioactivity is measured by its ability to inhibit SCF-dependent proliferation of TF-1 cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4, with 5% trehalose and containing 50 μg of BSA per 1 μg cytokine

Biochem/physiol Actions

Recombinant human stem cell factor soluble receptor (CD117, the gene product of the c-kit proto-oncogene) is a member of the class III subfamily of receptor tyrosine kinases. It binds SCF with high affinity and induces receptor homodimerization and signal transduction.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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