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S2439 Sigma

SNP and Microsatellite Genotyping: Markers for Genetic Analysis

  •  ISBN-10 1-88129-938-4

  •  ISBN-13 978-1-88129938-7



Related Categories Books and Software, Genetics Books, Labware, Molecular Biology Books
publication info   A. Hajeer, et al., ed., Eaton Publishing, 2000, 172 pp., hard cover
mfr. no.   Eaton Publishing


General description

Scientists are working to determine the genetic basis of disease. The aim of this book is to provide a reference manual to guide researchers in study design, selection of genetic markers (SNPs and microsatellites), genotyping methodologies, and basic analysis techniques. Topics covered include cytokine and cytokine receptor polymorphisms, high throughput analysis of SNP markers, new polymorphic microsatellite markers, large-scale genetic studies, DNA pooling strategy, linkage and association, and SNPs in gene mapping and DNA chip-based technologies (SNP Arrays).

Table of Contents

1. Conformational Analyses in the Detection and Genotyping of Polymorphisms: Application to Cytokine
2. MADGE and Other SNP Analysis Methods: Application Genes to the Molecular Genetic Epidemiology of Asthma and Cardiovascular Disease
3. Identification of Microsatellite Markers: Screening for Repeat Sequences and Mapping Polymorphisms
4. High Throughput Genotyping of Microsatellite Markers
5. DNA Pooling: Strategies for Microsatellite-based Association Studies
6. Data Analysis for Genetic Studies
7. Single Nucleotide Polymorphisms and Future Applications
Appendix: Selected Databases and Softwares for the Detection of SNPs In Silico

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