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S2626 Sigma

Spermidine

≥99% (GC)

Synonym: 1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience,
InChI Key   ATHGHQPFGPMSJY-UHFFFAOYSA-N
assay   ≥99% (GC)
form   solid or liquid (clear)
refractive index   n20/D 1.479(lit.)
density   0.925 g/mL at 25 °C(lit.)
storage temp.   room temp
Gene Information   rat ... Ppm1a(24666)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Caution

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Other Notes

Store under inert gas. Air sensitive; strongly hygroscopic.

Packaging

1, 5, 25 g in glass bottle

Application

Spermidine has been used:
• in the preparation of 5x transcription buffer
• in the treatment of double-stranded RNA along with other reagents to increase the uptake of dsRNA by nematodes
• as a standard in the analytical study of rat brain polyamines (185)

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

General description

The enzyme nitric oxide synthase (nNOS) is involved in the production of nitric oxide.

Price and Availability


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Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2735PSN2 8 / PGII
WGK Germany 
3
RTECS 
EJ7000000
Flash Point(F) 
233.6 °F
Flash Point(C) 
112 °C
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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Product #

Description

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709891 Spermidine-(butyl-d8) trihydrochloride, 98 atom % D, 95% (CP)
740780 Spermidine-(butyl-13C4) trihydrochloride, 99 atom % 13C, 95% (CP)

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