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  • S2657 - Monoclonal Anti-S-100 (β-Subunit) antibody produced in mouse

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S2657 Sigma

Monoclonal Anti-S-100 (β-Subunit) antibody produced in mouse

clone SH-B4, ascites fluid

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Neural Stem Cells, Antibodies for Stem Cell Biology,
species reactivity   human, sheep, rabbit, canine, bovine, pig, goat, feline, rat
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100 using protease-digested, formalin-fixed, paraffin-embedded human tongue sections
  indirect ELISA: suitable
clone   SH-B4, monoclonal
antibody form   ascites fluid
isotype   IgG1
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... S100B(6285)
rat ... S100b(25742)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

bovine brain S-100b

Specificity

Recognizes an epitope located on the β chain (i.e. in S-100a and S-100b) but not on the α chain of S-100 (i.e. in S-100a and S-100ao). In ELISA, recognition of S-100 subunit by clone SH-B4 is Ca2+-dependent. The product does not react with other members of the EF-hand family such as, calmodulin, parvalbumin, intestinal calcium-binding protein and myosin light chain. In immunohistochemistry, the antibody detects normal and neoplastic S-100 β subunit-containing cells (e.g. Schwann cells, chondrocytes, melanocytes, and melanotic tumors) in protease-digested, formalin-fixed, paraffin-embedded tissues.

Price and Availability


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