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S2941 Sigma

SKF-75670 hydrobromide

>98% (HPLC), solid

Synonym: 7,8-dihydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

  • Empirical Formula (Hill Notation) C17H19NO2 · HBr

  • Molecular Weight 350.25

  •  MDL number MFCD11045981

  •  PubChem Substance ID 24278700

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Description

Biochem/physiol Actions

Atypical D1 dopamine receptor agonist. Displays antagonist activity in vitro and agonist activity in vivo.

SKF-75670 is a selective dopamine D1 receptor agonist but with lower efficacy. It also acts as cocaine antagonist and alters the behavioral effects of cocaine in squirrel monkeys.

Application

SKF-75670 may be used in dopamine and cocaine-mediated cell signaling studies.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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