L-Serine ReagentPlus®, ≥99% (TLC)

Properties

Related Categories	Acacia, Allium cepa (Onion), Allium sativum (Garlic), Aloe Vera, Amino Acid, Amino Acid Derivatives, Amino Acid Library, Amino Acids, Amino acids, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chemical Biology, Chemical Synthesis, Core Bioreagents, Functional Foods, GABA and Glycine Receptor Modulators, Ginkgo biloba, Glycinergics, Hordeum vulgare (Barley), Humulus lupulus (Hops), Ion Channels, Ligand-Gated Ion Channels, Linum usitatissimum (Flax), Lipid, Lipid Library, Metabolic Libraries, Metabolic Pathways, Metabolites and Cofactors on the Metabolic Pathways Chart, Metabolomics, Neuroscience, Neurotransmission, Neurotransmitters, Nutrition Research, Ocimum basilicum (Basil), Panax ginseng, Peptide Chemistry, Phytochemicals by Plant (Food/Spice/Herb), Research Essentials, S, Serine, Zingiber officinale (Ginger) More...
grade	ReagentPlus^®
assay	≥99% (TLC)
mp	222 °C (dec.)(lit.)

Description

Biochem/physiol Actions

Precursor of glycine by serine hydroxymethyltransferase.

Packaging

1 kg in poly bottle

1, 100 g in poly bottle

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Related Papers

Structure elucidation and biosynthesis of fuscachelins, peptide siderophores from the moderate thermophile Thermobifida fusca. Eric J. Dimise et al Proc. Natl. Acad. Sci. U. S. A. 105, 15311-6, (2008)

Documents

Certificate of Analysis

Certificate of Origin

FT-IR Condensed Phase

FT-IR Raman

FT-NMR

S4500 - Product Information Sheet (36 KB)

Safety Information

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany	1

Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

Nucleotide Synthesis in Cancer Cells

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA. The metabolic pathways supporting nucl...
Keywords: Cancer, Catalysis, DNA replication, Gene expression, Glycolysis, Metabolic Pathways, Metabolism, Metabolites, Nucleotide Synthesis, PAGE, Pentose phosphate pathway, Pyrimidine synthesis

Papers

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Structure elucidation and biosynthesis of fuscachelins, peptide siderophores from the moderate thermophile Thermobifida fusca. Eric J. Dimise et al Proc. Natl. Acad. Sci. U. S. A. 105, 15311-6, (2008)

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Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5′-phosphate cofactor. Hoffman, H.E., et al. J. Med. Chem. 52, 6032-41, (2009)

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Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Olga Boudker et al Nature 445, 387-93, (2007)

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Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Griet Van Zeebroeck et al Nat. Chem. Biol. 5, 45-52, (2009)

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Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Iris Thondorf et al Bioorg. Med. Chem. 19, 6409-18, (2011)

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Merck 14,8460

Beil. 4,IV,3118

Fieser 12,430 / Fieser 14,282

Corp MSDS 1 (2), 3085:C / FT-IR 2 (1), 921:B / FT-IR 1 (1), 580:B / FT-NMR 1 (1), 880:A / IR-Spectra (3), 346:D / IR-Spectra (2), 308:G / RegBook 1 (1), 659:O / Sigma FT-IR 1 (1), 260:C / Structure Index 1, 98:A:2