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S5272 Sigma

Sulfanitran

~85%

Synonym: N4-Acetyl-N1-(4-nitrophenyl)sulfanilamide

  • CAS Number 122-16-7

  • Empirical Formula (Hill Notation) C14H13N3O5S

  • Molecular Weight 335.34

  •  Beilstein Registry Number 2952955

  •  MDL number MFCD00024598

  •  PubChem Substance ID 24899645

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics N-S, Biochemicals and Reagents
InChI Key   GWBPFRGXNGPPMF-UHFFFAOYSA-N
assay   ~85%
form   powder
color   yellow
Mode of action   enzyme | interferes

Description

Application

Sulfanitran is used to stimulate MRP2. It is used to stimulate the MRP2-mediated transport of lipophilic amphipathic drugs. It is used to study the efflux of chemotherapeutics in tumor cell lines.

Biochem/physiol Actions

Sulfanitran stimulates the ATP binding cassette family transporter multidrug resistance protein 2 (MRP2). Sulfanitran increases the affinity of MRP2 for estradiol-17-β-D-glucuronide. It stimulates the vectorial transport of saquinavir, a MRP2 substrate, across polarized MDCKII monolayers.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

HPLC Analysis of Antiprotozoal Drugs on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antiprotozoal Drugs on Ascentis® Phenyl
Keywords: Antibiotics, Antiprotozoals, Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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