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S5761 Sigma

Sodium bicarbonate

powder, BioReagent, for molecular biology, suitable for cell culture, suitable for insect cell culture

Synonym: Sodium hydrogen carbonate

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Properties

Related Categories Apoptosis and Cell Cycle, Biological Buffers, Buffers, Cell Biology, Cell Culture,
Quality Level   PREMIUM
grade   for molecular biology
InChI Key   UIIMBOGNXHQVGW-UHFFFAOYSA-M
product line   BioReagent
assay   99.5-100.5%
form   powder
quality   Premium
pH range   6.8 - 7.4
pKa (25 °C)   (1) 6.37, (2) 10.25 (carbonic acid)
solubility   water: soluble100 mg/mL
suitability   suitable for cell culture
  suitable for insect cell culture

Description

Packaging

1 kg in poly bottle

5 kg in poly drum

500 g in poly bottle

Application

Sodium bicarbonate has been used:
• as a component of bovine embryo culture system during in vitro maturation, fertilization, and culture (IVMFC)
• as a component of a 1:1 mixture of Dulbecco′s modified Eagle′s medium and Ham′s nutrient mixture F-12 during the culture of bovine microvascular endothelial cells
• as a component of ITS (insulin transferrin and selenite) medium used during the isolation of dopamine neurons from human embryonic stem cells
• as a component of medium used for cell culture of human embryonic kidney cells
• as a component of Beltsville thawing solution used for the dilution of semen

General description

Sodium bicarbonate is broadly used as a physiological buffer in cell culture applications. The pKa for bicarbonate <-> carbonic acid reaction is 6.4 The pKa for bicarbonate <-> carbonate reaction is 10.3. Sodum bicarbonate has two pKas, 6.4 and 10.3. It is broadly used as an physiological buffer in in vitro applications.

Price and Availability


Laboratory Gloves

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
VZ0950000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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S8761 Sodium bicarbonate solution, solution (7.5%), sterile-filtered, BioReagent, suitable for cell culture
S4019 Sodium bicarbonate, Hybri-Max, powder, suitable for hybridoma, ≥99.5%

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