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S6389 Sigma

1-Stearoyl-2-arachidonoyl-sn-glycerol

~98%, suitable for stimulation of protein kinase C derived from liver cells, liquid

Synonym: 1-Octadecanoyl-2-([cis,cis,cis,cis]-5,8,11,14-eicosatetraenoyl)-sn-glycerol, 2-Arachidonoyl-1-stearoyl-sn-glycerol

  • CAS Number 65914-84-3

  • Empirical Formula (Hill Notation) C41H72O5

  • Molecular Weight 645.01

  •  Beilstein Registry Number 2198923

  •  MDL number MFCD00070361

  •  PubChem Substance ID 24899699

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   NSXLMTYRMFVYNT-LGHBDAFPSA-N
assay   ~98%
form   liquid
impurities   1,3-isomer, trace
solubility   chloroform: soluble20 mg/ml
suitability   suitable for stimulation of protein kinase C derived from liver cells
shipped in   dry ice
storage temp.   −20°C

Description

Caution

This material may isomerize during storage.

Packaging

Sealed ampule

Application

1-Stearoyl-2-arachidonoyl-sn-glycerol was used to study Ca+2 signaling.5,6

Biochem/physiol Actions

1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacyl glycerol (DAG) that allosterically activates PKC and other proteins that affect cell growth, development, survival, apoptosis, carcinogenesis and metastasis.3 It activates transient receptor potential channels 3 and 6 that regulates the intracellular free calcium levels.4

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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94791 SnapIT Ampule Opener, Regular, for 1-2ml, 5-10ml, 10-15ml ampoules
43917 SnapIT Ampule Opener, large, for 5-10ml, 10-15ml, 20-25ml ampoules

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