|Related Categories||Bioactive Small Molecules, Biochemicals and Reagents, Catalysis and Inorganic Chemistry, Cell Biology, Cell Signaling and Neuroscience,|
|color||white to off-white|
Live Chat and Frequently Asked Questions are available for this Product.
Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.
Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25
10, 50, 250 g in poly bottle
Sodium orthovandate was used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase.26 It was one of the reagents used in the development of Matrix ChIP that utilizes surface-immobilized antibodies.27
Customers Also Viewed
Certificate of Analysis
Certificate of Origin
|Hazard statements||H302 + H312 + H332|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Faceshields, Gloves|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||20/21/22|
|Safety Statements (Europe)||22-36|
Protein tyrosine phosphatases (PTPs) and related enzymes (more than a hundred coded by the human genome) are more numerous than serine/threonine phosphatases. They belong to four families, three of w...
Keywords: Adhesion, Cancer, Catalysis, Diabetes, Gene expression, Ligands, Phosphorylations
Vanadate stimulates system A amino acid transport activity in skeletal muscle: Evidence for the involvement of intracellular pH as a mediator of vanadate action. Munoz, P., et al. J. Biol. Chem. 267, 10381, (1992)
Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants. Wälchli S, Curchod ML, Gobert RP, et al. J. Biol. Chem. 275(13), 9792-6, (2000)
Triptolide Inhibits the Proliferation of Immortalized HT22 Hippocampal Cells Via Persistent Activation of Extracellular Signal-Regulated Kinase-1/2 by Down-Regulating Mitogen-Activated Protein Kinase Phosphatase-1 Expression. Koo HS J. Korean Neurosurg. Soc. 46(4), 389-96, (2009)
Corp MSDS 1 (2), 3148:D / FT-IR 2 (3), 4766:C / FT-IR 1 (2), 1290:A / IR-Spectra (3), 270:G / RegBook 1 (3), 3467:B / Sax 6, 2458 / Sigma FT-IR 1 (2), 1045:C
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?