EMAIL THIS PAGE TO A FRIEND
S6826 Sigma

Stiripentol

≥98% (HPLC)

Synonym: 4,4-dimethyl-1-[3,4(methylenedioxy)-phenyl]-1-penten-3-ol, Diacomit

Purchase

Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, S
InChI Key   IBLNKMRFIPWSOY-FNORWQNLSA-N
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: ≥20 mg/mL
storage temp.   −20°C

Description

Biochem/physiol Actions

Anti-convulsant drug

Stiripentol is an anti-epileptic compound that inhibits CYP3A4, CYP1A2, and CYP2C19 in vivo in epileptic patients. Because of its inhibitory effect on cytochrome P450, it is known to inhibit the metabolism of clobazam, another anti-epileptic agent.1 It enhances the release of GABA and prolongs the GABAA receptor-mediated currents in rat hippocampal neurons.2 Stiripentol is an efficacious drug in treating severe myoclonic epilepsy in infancy.1,3

Application

Stiripentol may be used in GABAA receptor-mediated cell signaling studies.

Price and Availability


DISCOVER Bioactive Small Molecules

Making Headway

All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?