|Related Categories||Biochemicals and Reagents, Detergents, Detergents N to Z, Non-Ionic Detergents|
Span® 60 is a sorbitan monoester than is used as a non-ionic detergent. 3
Fatty acid composition: Stearic acid (C18:0) approx. 50%; balance primarily palmitic acid (C16:0).
1 kg in poly bottle
250 g in poly bottle
Span® 60 has been used in a study to assess encapsulation of doxorubicin in niosomes as a route to tumor targeting. 1 It has also been used in a study to investigate the use of nonionic surfactants as contrast agents for use in diagnostic ultrasounds. 2
Span is a registered trademark of Croda International PLC
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2. Surfactant-stabilized microbubbles as ultrasound contrast agents: stability study of [TM="Span"] 60 and Tween 80 mixtures using a Langmuir trough Singhal, S., et al. Langmuir 9, 2426, (1993)
3. Preparation and properties of vesicles (niosomes) of sorbitan monoesters ([TM="Span"] 20, 40, 60 and 80) and a sorbitan triester ([TM="Span"] 85). Yoshioka, T., et al. Int. J. Pharm. 105, 1, (1994)
Comparative study on the effects of some polyoxyethylene alkyl ether and sorbitan fatty acid ester surfactants on the performance of transdermal carvedilol proniosomal gel using experimental design. Aboelwafa AA, El-Setouhy DA, and Elmeshad AN AAPS PharmSciTech 11(4), 1591-602, (2010)
An investigation into the role of surfactants in controlling particle size of polymeric nanocapsules containing penicillin-G in double emulsion. Khoee S and Yaghoobian M Eur. J. Med. Chem. 44(6), 2392-9, (2009)
Fatty alcohols or fatty acids as niosomal hybrid carrier: effect on vesicle size, encapsulation efficiency and in vitro dye release. Bandyopadhyay P and Johnson M Colloids Surf. B Biointerfaces 58(1), 68-71, (2007)
Improved photostability and reduced skin permeation of tretinoin: development of a semisolid nanomedicine. Ourique AF, Melero A, de Bona da Silva C, et al. Eur. J. Pharm. Biopharm. 79(1), 95-101, (2011)
Evidence for vesicle formation from 1:1 nonionic surfactant span 60 and fatty alcohol mixtures in aqueous ethanol: potential delivery vehicle composition. Bandyopadhyay P and Neeta NS Colloids Surf. B Biointerfaces 58(2), 305-8, (2007)
[9-nitrocamptothecin nanostructured lipid carrier system: in vitro releasing characteristics, uptake by cells, and tissue distribution in vivo]. Li JC, Sha XY, Zhang LJ, et al. Yao Xue Xue Bao 40(11), 970-5, (2005)
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