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S7576 Sigma

Shikonin

≥98% (HPLC)

Synonym: (±)-Alkannin, (±)-Shikalkin, (±)-Shikonin, (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone

Properties

Related Categories Cell Biology, Nutrition Research, Phenols, Phytochemicals by Chemical Classification, Phytochemicals in Herbal Medicine or Traditional Chinese Medicine (TCM) More...
assay   ≥98% (HPLC)
form   powder or solid
color   red to brown
solubility   methanol: soluble1 mg/mL
storage temp.   2-8°C

Description

Packaging

10 mg in glass bottle

50 mg in poly bottle

Biochem/physiol Actions

Naphthoquinone isolated from Arnebia sp. Used as an anti-inflammatory treatment in traditional chinese medicine (TCM). Inhibits chemokine receptor function and suppresses HIV-1.† Circumvents cancer drug resistance by induction of cell death through a necroptotic pathway.† Treatment of cancer cells with shikonin suppressed glycolysis via the inhibition of pyruvate kinase M2 (PKM2).

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