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S7796 Sigma

Sisomicin sulfate salt

≥80% (TLC)

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Properties

Related Categories Aminoglycosides, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S,
InChI Key   CIKNYWFPGZCHDL-ZHFUJENKSA-N
assay   ≥80% (TLC)
form   powder
optical activity   [α]25/D 100 to 110° in water (Specific rotation (anhydrous), C=1)
color   white to off-white
solubility   H2O: soluble 50 mg/mL
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
storage temp.   2-8°C

Description

Packaging

1, 5 g in glass bottle

250 mg in glass bottle

250MG,1G,5G

Application

Sisomicin is an aminoglycoside antibiotic isolated from Micromonopora inyoensis. It is effective against most strains of Klebsiellk spp., Escherichia coli, P. aeruginosa, Enterobacter and Proteus spp.. It is a potential treatment for conjunctiva . It is used in disk and tube dilution sensitivity test.

Biochem/physiol Actions

Sisomicin interferes with protein synthesis at the level of functional ribosome assembly. The mechanism is similar to that of gentamycin. Sisomicin closely resembles gentamicin but is more effective against Pseudomonas aeruginosa and indole-positive Proteus.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
WK2288000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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