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S8065 Sigma

Amyloid Precursor Protein α (304-612), Secreted human

>90% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), buffered aqueous solution

Synonym: sAPPα (304-612)

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Properties

Related Categories Alzheimer′s Disease, Amyloid Precursor Proteins and Fragments, Cell Biology, Cell Signaling and Neuroscience, Neurobiology,
recombinant   expressed in E. coli (N-terminal histidine tagged)
assay   >90% (SDS-PAGE)
form   buffered aqueous solution
mol wt   apparent mol wt ~45 kDa by SDS-PAGE
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... APP(351)

Description

Packaging

25 μg in glass bottle

Preparation Note

Expressed as a soluble protein and purified under non-denaturing conditions.

Physical form

0.2 μm filtered solution in phosphate buffered saline, pH 7.4.

Biochem/physiol Actions

Secreted Amyloid Precursor Protein α (sAPPα) is a 612 amino acid protein produced from the ubiquitously expressed β-Amyloid precursor protein (βAPP), 695 isoform, by α-secretase cleavage. sAPPα (304-612) is a fragment of sAPPα designed to lack the N-terminal domain of the full length protein.

Price and Availability


Amplified Detection

Neuroscience Grant Programm

Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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