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S9129 Sigma

Somatostatin

≥97% (HPLC), powder

Synonym: Growth hormone release inhibiting factor, SRIF, Somatostatin-14, Somatotropin release inhibiting factor

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology,
InChI Key   NHXLMOGPVYXJNR-FQSIDJEASA-N
assay   ≥97% (HPLC)
form   powder
storage temp.   −20°C
Gene Information   human ... SSTR1(6751), SSTR2(6752), SSTR3(6753), SSTR4(6754), SSTR5(6755)

Description

Amino Acid Sequence

Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys

Other Notes

Lyophilized from 0.1% TFA in H2O

Packaging

1, 5, 10 mg in glass bottle

Application

Somatostatin has been used:
• as a standard antigen to detect antibodies in an indirect enzyme-linked immunosorbent assay (ELISA) method
• to study the effect of somatostatin on oxytocin release during pregnancy in rats
• to test the specificity of the avidin-biotinylated horseradish peroxidase immunocytochemical procedure to visualize somatostatin-immunoreactive (SS-IR) neurons

Biochem/physiol Actions

Somatostatin regulates the secretion of hormones and bioactive peptides. It acts as an inhibitor in the digestive tract by inhibiting gastrin release. In the pancreatic islets, it inhibits glucagon and insulin release. Somatostatin and its synthetic analogs have been used in the treatment of neuroendocrine tumors.

General description

Somatostatin is expressed in endocrine cells and nerve fibers of the gastrointestinal tract. It is also expressed in other tissues.

Price and Availability


Making Headway

All labs need water

Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
WF8751700

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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