Sphingosine 1-phosphate
≥95%, powder
DOWNLOAD MSDS (PDF)Synonym:
(2S,3R,4E)
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CAS Number 26993-30-6
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Empirical Formula (Hill Notation) C18H38NO5P
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Molecular Weight 379.47
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MDL number MFCD00270077
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PubChem Substance ID 24899853
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Popular Documents: Product Information Sheet (PDF) | Specification Sheet (PDF)
Properties
| Related Categories | Angiogenesis, Angiogenic Factors, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research, |
| Quality Level | PREMIUM |
| assay | ≥95% |
| form | powder |
| storage temp. | −20°C |
| Gene Information | human ... S1PR1(1901), S1PR2(9294), S1PR3(1903), S1PR4(8698), S1PR5(53637) |
Description
Biochem/physiol Actions
A lipid second messenger that binds to S1P1 and S1P3 receptors. Mobilizes intracellular Ca2+ stores and decreases cellular cAMP. Activates phospholipase D. S1P stimulates the migration of endothelial cells but inhibits the migration of other cell types. Induces angiogenesis.
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