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SAB1100909 Sigma

Anti-FGF19 (121-133) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-Fibroblast growth factor 19 precursor



Related Categories Alphabetical Index, Antibodies, FB-FJ, Primary Antibodies
species reactivity   human
application(s)   indirect immunofluorescence: suitable
  western blot: 1:500-1:2,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~24 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... FGF19(9965)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acids 121-133 of human FGF19

General description

Fibroblast growth factor-19 (FGF-19) is an ileum-derived polypeptide hormone and a high affinity heparin-dependent ligand for fibroblast growth factor receptor 4 (FGFR4). It is part of the hormone-like FGF family. The gene encoding FGF-19 is localized on human chromosome 11q13.3.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Biochem/physiol Actions

Fibroblast growth factor-19 (FGF-19) is involved in the gut-liver signaling pathway and modulation of bile acid synthesis. Once secreted, it binds to the hepatic fibroblast growth factor receptor 4 (FGFR4)/Klotho-β cell-surface receptor complex and activates it. FGF-19 promotes glycogen synthesis, protein synthesis and lipid metabolism.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
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