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SAB1306351 Sigma

ANTI-PKC ETA(N-TERMINAL) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: PKC-L, PKCL, PRKCH, PRKCL, Protein kinase C eta type

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Properties

Related Categories Alphabetical Index, Antibodies, PJ-PN, Primary Antibodies
species reactivity   human
application(s)   immunohistochemistry: 1:50-1:100
  western blot: 1:1000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   mol wt 77828 Da
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... PRKCH(5583)
biological source   rabbit
NCBI accession no.   NP_006246.2
UniProt accession no.   P24723

Description

General description

Protein kinase C η (PKCL) is expressed in epithelial tissues. It is part of the protein kinase C family. The protein is localized at the Golgi apparatus, nuclear envelope and endoplasmic reticulum. The gene encoding PKCL is located on human chromosome 14q22-q23.

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

Biochem/physiol Actions

Protein kinase C η (PKCL) has a role in differentiation and proliferation of cells. The protein activates IκB kinase (IKK) and modulates nuclear factor κB (NF-κB) upstream signaling. It also has a role in the transcriptional activation of the transglutaminase 1 gene.

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Safety Information

RIDADR  NONH for all modes of transport
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Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

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