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SAB1400153 Sigma

Monoclonal Anti-LMNB1 antibody produced in mouse

clone 4B10, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-ADLD, Anti-LMN2, Anti-LMN, Anti-LMNB, Anti-MGC111419

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Properties

Related Categories Alphabetical Index, Antibodies, LM-LRP, Primary Antibodies
species reactivity   human
application(s)   immunofluorescence: suitable
  immunoprecipitation: suitable
  indirect ELISA: suitable
  western blot: suitable
clone   4B10, monoclonal
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG2aκ
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... LMNB1(4001)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

LMNB1 (NP_005564.1, 107 a.a. ~ 186 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLAD

General description

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. (provided by RefSeq)

Physical form

Solution in phosphate buffered saline, pH 7.4

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Safety Information

RIDADR  NONH for all modes of transport
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Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

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