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  • SAB2105004 - Anti-PRKAB1, (N-terminal) antibody produced in rabbit

SAB2105004 Sigma

Anti-PRKAB1, (N-terminal) antibody produced in rabbit

affinity isolated antibody

Synonym: Anti-AMPK, Anti-HAMPKb, Anti-MGC17785



Related Categories Alphabetical Index, Antibodies, PR-PR, Primary Antibodies
species reactivity   rabbit, mouse, human, guinea pig, horse
application(s)   western blot: suitable
clone   polyclonal
concentration   0.5 mg - 1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   mol wt 30 kDa
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... PRKAB1(5564)
biological source   rabbit
conjugate   unconjugated
NCBI accession no.   NM_006253



The immunogen for anti-PRKAB1 antibody: synthetic peptide derected towards the N terminal of human PRKAB1

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.


Anti-PRKAB1, (N-terminal) antibody produced in rabbit is suitable for western blot analysis.

Biochem/physiol Actions

PRKAB1 (protein kinase, AMP-activated, β 1 non-catalytic subunit) is a non-catalytic, β subunit of AMP-activated protein kinase (AMPK). It acts as a metabolic sensor for AMP levels. It plays a key role in energy sensor during the response to energy demand and supply. It regulates cell metabolism. It increases the glycolytic flux by H202 which increase intracellular NADPH content. The activity of PRKAB1 is controlled by decreasing concentrations of adenosine triphosphate (ATP) and increasing AMP concentrations.


Synthetic peptide located within the following region: KILMDSPEDADLFHSEEIKAPEKEEFLAWQHDLEVNDKAPAQARPTVFRW

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  3
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