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SAB2500052 Sigma

Anti-AKAP9/AKAP450/CG-NAP antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym: Anti- PRKA9, Anti-AKAP350, Anti-CG-NAP, Anti-Hyperion, Anti-YOTIAO

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Properties

Related Categories AE-AK, Alphabetical Index, Antibodies, Primary Antibodies
species reactivity   human
application(s)   indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... AKAP9(10142)
biological source   goat
conjugate   unconjugated

Description

Immunogen

Peptide with sequence C-SGSTTQFHAGMR from the C Terminus of the protein sequence according to NP_671700.1; NP_005742.4; NP_671714.1.

General description

The gene encoding A-kinase anchoring protein 9 (AKAP9) is localized to human chromosome 7q21–q22. It is a 350-450kDa protein present in the centrosomes and the Golgi apparatus.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Biochem/physiol Actions

A-kinase anchoring protein 9 (AKAP9) is used by cells to anchor the regulatory subunit of type II cAMP-dependent protein kinase A. It coordinates multiple intracellular signaling events and scaffolds protein kinases and phosphatases at the centrosome and the Golgi apparatus. The protein interacts with cdc42 interacting protein 4 (CIP4) at the Golgi apparatus and functions in the maintenance of normal structure of Golgi apparatus.

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Safety & Documentation

Safety Information

Symbol  GHS07  GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P305 + P351 + P338
RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

Articles

Phase I Drug Metabolism

Phase I biotransformation reactions introduce or expose functional groups on the drug with the goal of increasing the polarity of the compound. Although Phase I drug metabolism occurs in most tissues...
Robert Gates
Biofiles Volume 6 Article 1
Keywords: Catalysis, Eliminations, Environmental, Enzyme-linked immunosorbent assay, Gastrointestinal, Gene expression, Immunohistochemistry, Metabolism, Metabolites, Oxidations, Post translational modifications, Reductions, Support, Western blot

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Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
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Peer-Reviewed Papers
15

References

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