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SAB2501104 Sigma

Anti-VPS28 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-MGC60323, Anti-Vacuolar protein sorting 28, Anti-Yeast class E protein Vps28p homolog



Related Categories Alphabetical Index, Antibodies, Primary Antibodies, V
species reactivity   mouse, rat, human, canine
application(s)   immunohistochemistry: suitable
  immunohistochemistry: suitable
  indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... VPS28(51160)
biological source   goat
conjugate   unconjugated



Peptide with sequence C-ESAYNAFNRFLHA from the C Terminus of the protein sequence according to NP_057292.1.

General description

The gene VPS28 (vacuolar protein sorting-associated protein 28 homolog) is mapped to human chromosome 8q24.3. The encoded protein is part of the ESCRT-1 (endosomal complexes required for transport) complex. The complex participates in membrane remodelling, including multivesicular body biogenesis and cytokinesis.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Biochem/physiol Actions

VPS28 (vacuolar protein sorting-associated protein 28 homolog) participates in various cellular events, including OGD/R (oxygen and glucose deprivation followed by reoxygenation)-mediated neuronal cell death, peptide growth factors-initiated SOS1 (son of sevenless 1)-Ras signaling, epithelial-mesenchymal transition and cell invasion.

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Safety & Documentation

Safety Information

Symbol  GHS07  GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P305 + P351 + P338
RIDADR  NONH for all modes of transport
WGK Germany  2
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Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

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