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  • SAB3500070 - Anti-THEM2 antibody produced in rabbit

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SAB3500070 Sigma

Anti-THEM2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-ACOT13, Anti-Acyl-CoA thioesterase 13, Anti-PNAS-27, Anti-Thioesterase superfamily member 2

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies with Corresponding Blocking Peptides, Primary Antibodies, T,
species reactivity   human, rat, mouse
application(s)   immunofluorescence: suitable
  immunohistochemistry: suitable
  indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... ACOT13(55856)
biological source   rabbit
conjugate   unconjugated
NCBI accession no.   NP_060943
UniProt accession no.   Q9NPJ3

Description

Immunogen

THEM2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THEM2.

Antigen Background

THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500070.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
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SBP3500070 THEM2 Blocking Peptide for SAB3500070

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